Christa Schleper Explained
Christa Schleper is a German microbiologist known for her work on the evolution and ecology of Archaea. Schleper is Head of the Department of Functional and Evolutionary Biology at the University of Vienna in Austria.
Life and education
Having initially gone to university to study languages and economics, Schleper eventually switched to studying biology.[2] She received a Ph.D. at the Max Planck Institute of Biochemistry in 1995 and subsequently did postdoctoral research at the Monterey Bay Aquarium Research Institute.[3]
Work and discoveries
Schleper is known for research advancing understanding of uncultivated Archaea in marine and terrestrial systems. Schleper's early research on Sulfolobus was the first research to indicate the presence of a virus in a thermophilic Archaea.[4] Schleper went on to isolate multiple thermophilic Archaea capable of growth under acidic conditions,[5] [6] and led 16S RNA surveys to define the distribution of crenarchaeota in terrestrial environments.[7] During postdoctoral research, Schleper used biochemical information from a low-temperature crenarchaeota to propose a non-thermophilic origin for these crenarchaeota, a novel idea at the time it was proposed in 1997.[8] Schleper's more recent research has advanced understanding of ammonia-oxidizing thaumarchaeota.[9] [10] The research into ammonia-oxidizing archaea used the newly-isolated Nitrososphaera viennensis EN76 to provide the first description of the genes and proteins shared by terrestrial and marine ammonia-oxidizing archaea.[11] [12] Schleper's research on Lokiarchaeota[13] provides a platform to examine the evolution of life from single celled organisms into complex, multicellular organisms.[14]
Schleper has three patents granted: Isolation and cloning of DNA from uncultivated organisms,[15] Archaeon expression system[16] and Nucleic acids and proteins from Cenarchaeum symbiosum.[17]
Awards and recognition
Notes and References
- https://archaea.univie.ac.at/fileadmin/user_upload/p_archaea/people/Schleper/CV_Schleper_2020_9_webpage.pdf
- Web site: Pioneer in archaea research (Christa Schleper) . YouTube . 3 November 2023 . en.
- Book: Albers, Sonja-Verena . Christa Schleper: Enthusiasm and Insight in the World of Archaea . American Society for Microbiology . 2018 . Washington, DC . 253–256 . Sonja-Verena Albers.
- Schleper. C.. Kubo. K.. Zillig. W.. 1992-08-15. The particle SSV1 from the extremely thermophilic archaeon Sulfolobus is a virus: demonstration of infectivity and of transfection with viral DNA.. Proceedings of the National Academy of Sciences. en. 89. 16. 7645–7649. 10.1073/pnas.89.16.7645. 0027-8424. 49767. 1502176. 1992PNAS...89.7645S. free.
- Schleper. Christa. 1995. Picrophilus gen. nov., fam. nov.: a novel aerobic, heterotrophic, thermoacidophilic genus and family comprising archaea capable of growth around pH 0.. Journal of Bacteriology. 177. 24. 7050–7059. 10.1128/jb.177.24.7050-7059.1995. 8522509. 177581.
- Schleper. Christa. Piihler. Gabriela. Kuhlmorgen. Brigitte. Zillig. Wolfram. June 1995. Life at extremely low pH. Nature. en. 375. 6534. 741–742. 10.1038/375741b0. 7541113. 1995Natur.375..741S. 4341809. 1476-4687.
- Quaiser. Achim. Ochsenreiter. Torsten. Lanz. Christa. Schuster. Stephan C.. Treusch. Alexander H.. Eck. Jürgen. Schleper. Christa. 2003. Acidobacteria form a coherent but highly diverse group within the bacterial domain: evidence from environmental genomics. Molecular Microbiology. en. 50. 2. 563–575. 10.1046/j.1365-2958.2003.03707.x. 14617179. 25162803. 1365-2958.
- Schleper. C. Swanson. R V. Mathur. E J. DeLong. E F. 1997. Characterization of a DNA polymerase from the uncultivated psychrophilic archaeon Cenarchaeum symbiosum.. Journal of Bacteriology. en. 179. 24. 7803–7811. 10.1128/JB.179.24.7803-7811.1997. 0021-9193. 179745. 9401041.
- Leininger. S.. Urich. T.. Schloter. M.. Schwark. L.. Qi. J.. Nicol. G. W.. Prosser. J. I.. Schuster. S. C.. Schleper. C.. 2006. Archaea predominate among ammonia-oxidizing prokaryotes in soils. Nature. en. 442. 7104. 806–809. 10.1038/nature04983. 16915287. 2006Natur.442..806L. 4380804. 1476-4687.
- Tourna. Maria. Stieglmeier. Michaela. Spang. Anja. Könneke. Martin. Schintlmeister. Arno. Urich. Tim. Engel. Marion. Schloter. Michael. Wagner. Michael. Richter. Andreas. Schleper. Christa. 2011-05-17. Nitrososphaera viennensis, an ammonia oxidizing archaeon from soil. Proceedings of the National Academy of Sciences. en. 108. 20. 8420–8425. 10.1073/pnas.1013488108. 0027-8424. 3100973. 21525411. 2011PNAS..108.8420T. free.
- Kerou. Melina. Offre. Pierre. Valledor. Luis. Abby. Sophie S.. Melcher. Michael. Nagler. Matthias. Weckwerth. Wolfram. Schleper. Christa. 2016-12-06. Proteomics and comparative genomics of Nitrososphaera viennensis reveal the core genome and adaptations of archaeal ammonia oxidizers. Proceedings of the National Academy of Sciences. en. 113. 49. E7937–E7946. 10.1073/pnas.1601212113. 0027-8424. 5150414. 27864514. 2016PNAS..113E7937K . free.
- Web site: Which genes are crucial for the energy metabolism of Archaea?. 2021-04-26. EurekAlert!. en.
- Spang. Anja. Saw. Jimmy H.. Jørgensen. Steffen L.. Zaremba-Niedzwiedzka. Katarzyna. Martijn. Joran. Lind. Anders E.. van Eijk. Roel. Schleper. Christa. Guy. Lionel. Ettema. Thijs J. G.. 2015. Complex archaea that bridge the gap between prokaryotes and eukaryotes. Nature. en. 521. 7551. 173–179. 10.1038/nature14447. 1476-4687. 4444528. 25945739. 2015Natur.521..173S.
- Web site: Lokiarchaeota and the Origin of Complex Life. 2021-04-26. Quanta Magazine. en.
- US . US7749366. 2010-07-06. Isolation and cloning of DNA from uncultivated organisms. Biotechnology Research and Information Network AG. Quaiser. Achim. Ochsenreiter. Torsten. Treusch. Alexander H.. Kletzin, Arnulf;Schleper, Christa;Lorenz, Patrick;Eck, Jürgen.
- EP. 1629100. 2010-09-15. Archaeon expression system. Biotechnology Research and Information Network AG. Schleper. Christa. Jonuscheit. Melanie. Eck. Jürgen . Frank Niehaus;Sonja-Verena Albers;Sabrina Froels.
- WO. 0018909. 2000-07-27. Nucleic acids and proteins from Cenarchaeum symbiosum. Diversa Corp.. Swanson. Ronald V.. Feldman. Robert A.. Schleper. Christa.
- Web site: Find an EMBO Young Investigator / EMBO Installation Grantee / EMBO Global Investigator. 2021-05-05. yip-search.embo.org.
- Web site: American Academy of Microbiology Fellows. live. https://web.archive.org/web/20190104191743/https://www.asm.org/Academy/Academy . 2019-01-04 .
- Web site: ÖAW Mitglieder Detail. 2021-05-05. www.oeaw.ac.at.
- Web site: Mikrobiologin Christa Schleper erhält den diesjährigen "Austro-Nobelpreis" . . 22 June 2022 . de . 23 June 2022.