Chorangiosis Explained

Chorangiosis
Field:	Pathology

Chorangiosis is a placental pathology characterized by an abundance of blood vessels within the chorionic villi.

Associations

It is associated with gestational diabetes,^[1] smoking and high altitude.

Diagnosis

It is diagnosed by a microscopic examination of the placenta.

Commonly used criteria from Altshuler^[2] are: "a minimum of 10 villi, each with 10 or more vascular channels, in 10 or more areas of 3 or more random, non-infarcted placental areas when using a ×10 ocular." The Altshuler criteria are not theoretically rigorous, as they do not define the area. Normal villi have up to five vascular channels.^[3]

See also

• Chorangioma

Notes and References

1. Daskalakis . G. . Marinopoulos . S. . Krielesi . V. . Papapanagiotou . A. . Papantoniou . N. . Mesogitis . S. . Antsaklis . A. . Placental pathology in women with gestational diabetes. . Acta Obstet Gynecol Scand . 87 . 4 . 403–7 . 2008 . 10.1080/00016340801908783 . 18382864 . 43058233 . free .
2. Altshuler . G. . Chorangiosis. An important placental sign of neonatal morbidity and mortality. . Arch Pathol Lab Med . 108 . 1 . 71–4 . Jan 1984 . 6546343 .
3. De La Ossa . MM. . Cabello-Inchausti . B. . Robinson . MJ. . Placental chorangiosis. . Arch Pathol Lab Med . 125 . 9 . 1258 . Sep 2001 . 10.5858/2001-125-1258-PC. 11520290 .