Chondro-4-sulfatase explained
| Chondro-4-sulfatase |
| Ec Number: | 3.1.6.9 |
| Cas Number: | 9045-75-4 |
The enzyme chondro-4-sulfatase (EC 3.1.6.9)[1] [2] [3] catalyzes the reaction
4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-N-acetyl-D-galactosamine 4-sulfate + H2O
4-deoxy-β-
D-gluc-4-enuronosyl-(1→3)-
N-acetyl-
D-galactosamine + sulfate
This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name is 4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase. This enzyme is also called chondroitin-4-sulfatase.
Notes and References
- Held E, Buddecke E . 1967 . [Studies on the chemistry of the arterial wall, XI. Demonstration, purification and properties of a chondroitin-4-sulfatase from bovine aorta] . Hoppe-Seyler's Z. Physiol. Chem. . 348 . 1047 - 60 . 5595107 . 8 .
- Roy AB . 1976 . Sulphatases, lysosomes and disease . Aust. J. Exp. Biol. Med. Sci. . 54 . 111 - 35 . 13772 . 10.1038/icb.1976.13 . 2 .
- Yamagata T, Saito H, Habuchi O, Suzuki S . 1968 . Purification and properties of bacterial chondroitinases and chondrosulfatases . J. Biol. Chem. . 243 . 1523 - 35 . 5647268 . 7 .
