Choline sulfotransferase explained

choline sulfotransferase
Ec Number:2.8.2.6
Cas Number:9047-23-8
Go Code:0047754

In enzymology, a choline sulfotransferase is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + choline

\rightleftharpoons

adenosine 3',5'-bisphosphate + choline sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and choline, whereas its two products are adenosine 3',5'-bisphosphate and choline sulfate.[1]

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:choline sulfotransferase. This enzyme is also called choline sulphokinase. This enzyme participates in sulfur metabolism.

Notes and References

  1. Orsi BA, Spencer B. Tokyo . Choline sulphokinase (sulphotransferase) . J. . Biochem. . 81 - 91 .