Cholestenol Delta-isomerase explained

Cholestenol Δ-isomerase
Ec Number:	5.3.3.5
Cas Number:	37318-47-1
Go Code:	0047750

In enzymology, a cholestenol Δ-isomerase is an enzyme that catalyzes the chemical reaction

5alpha-cholest-7-en-3beta-ol

\rightleftharpoons 5alpha-cholest-8-en-3beta-ol

Hence, this enzyme has one substrate, 5alpha-cholest-7-en-3beta-ol, and one product, 5alpha-cholest-8-en-3beta-ol.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is Delta7-cholestenol Delta7-Delta8-isomerase. This enzyme participates in biosynthesis of steroids.

See also

• Emopamil binding protein

References

• Wilton DC, Rahimtula AD, Akhtar M . The reversibility of the delta8-cholestenol-delta7-cholestenol isomerase reaction in cholesterol biosynthesis . The Biochemical Journal . 114 . 1 . 71–73 . August 1969 . 5810070 . 1184797 . 10.1042/bj1140071 .