Type: | combo |
Component1: | Chlorproguanil |
Class1: | Antimalarial drug |
Component2: | Dapsone |
Class2: | Antibiotic |
Legal Status: | Withdrawn |
Cas Number: | 209665-78-1 |
Chlorproguanil/dapsone (sold commercially as Lapdap) was a fixed dose antimalarial combination containing chlorproguanil and dapsone,[1] which act synergistically against malaria. The drug was withdrawn in 2008 following increasing evidence of toxicity in the form of haemolysis occurring in patients with G6PD deficiency.[2]