| chloromuconate cycloisomerase | |
| Ec Number: | 5.5.1.7 |
| Cas Number: | 95990-33-3 |
| Go Code: | 0018850 |
| Width: | 270 |
In enzymology, a chloromuconate cycloisomerase is an enzyme that catalyzes the chemical reaction
2-chloro-2,5-dihydro-5-oxofuran-2-acetate
\rightleftharpoons
Hence, this enzyme has one substrate, 2-chloro-2,5-dihydro-5-oxofuran-2-acetate, and one product, 3-chloro-cis,cis-muconate.
This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. The systematic name of this enzyme class is 2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing). This enzyme is also called muconate cycloisomerase II. This enzyme participates in gamma-hexachlorocyclohexane degradation and 1,4-dichlorobenzene degradation. It employs one cofactor, manganese.
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes,, and .