Chlorobi-RRM RNA motif explained

Chlorobi-RRM RNA
Symbol:Clorobi-RRM
Rfam:RF01697
Rna Type:Cis-regulatory element
Tax Domain:Chlorobiota

The Chlorobi-RRM RNA motif is a conserved RNA structure identified by bioinformatics.[1] It is found within bacteria in the phylum Chlorobiota (formerly Chlorobi), and is exclusively detected in the presumed 5' untranslated regions (5' UTRs) of genes that encode putative RNA-binding proteins. Since many RNA-binding proteins regulate their own expression in a feedback mechanism by binding or acting up their 5' UTR, it was proposed that the Chlorobi-RRM is a component in an analogous feedback mechanism.Structurally, the motif consists of two stem-loops, the second of which might function as a rho-independent transcription terminator.

Notes and References

  1. Weinberg Z, Wang JX, Bogue J . Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes . Genome Biol . 11 . 3 . R31 . March 2010 . 20230605 . 10.1186/gb-2010-11-3-r31 . 2864571. etal . free .