Chlorisondamine Explained

Chlorisondamine is a nicotinic acetylcholine receptor antagonist that produces both neuronal and ganglionic blockade.

Chlorisondamine has been shown to form noncovalent complexes with various biomolecules including sphingomyelin and other associated glycolipids.^{[1] [2] [3]}

Notes and References

1. Woods AS, Moyer SC, Wang HY, Wise RA . Interaction of chlorisondamine with the neuronal nicotinic acetylcholine receptor . Journal of Proteome Research . 2 . 2 . 207–12 . 2003 . 12716135 . 10.1021/pr025578h .
2. Jackson SN, Wang HY, Woods AS, Ugarov M, Egan T, Schultz JA . 5894935 . Direct tissue analysis of phospholipids in rat brain using MALDI-TOFMS and MALDI-ion mobility-TOFMS . Journal of the American Society for Mass Spectrometry . 16 . 2 . 133–8 . February 2005 . 15694763 . 10.1016/j.jasms.2004.10.002 . free .
3. Woods AS, Ugarov M, Egan T, Koomen J, Gillig KJ, Fuhrer K, Gonin M, Schultz JA . Lipid/peptide/nucleotide separation with MALDI-ion mobility-TOF MS . Analytical Chemistry . 76 . 8 . 2187–95 . April 2004 . 15080727 . 10.1021/ac035376k .