Chitosanase Explained

Chitosanase
Ec Number:	3.2.1.132
Cas Number:	51570-20-8

Chitosanase is an enzyme with systematic name chitosan N-acetylglucosaminohydrolase.^{[1] [2] [3] [4]} This enzyme catalyses the following chemical reaction

Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan

A whole spectrum of chitosanases are known.

Notes and References

1. Purification and mode of action of a chitosanase from Penicillium islandicum . Fenton DM, Eveleigh DE . J. Gen. Microbiol. . 1981 . 126 . 151–165 . 10.1099/00221287-126-1-151. free .
2. Saito J, Kita A, Higuchi Y, Nagata Y, Ando A, Miki K . Crystal structure of chitosanase from Bacillus circulans MH-K1 at 1.6-A resolution and its substrate recognition mechanism . The Journal of Biological Chemistry . 274 . 43 . 30818–25 . October 1999 . 10521473 . 10.1074/jbc.274.43.30818 . free .
3. Izume M, Nagae S, Kawagishi H, Mitsutomi M, Ohtakara A . Action pattern of Bacillus sp. no. 7-M chitosanase on partially N-acetylated chitosan . Bioscience, Biotechnology, and Biochemistry . 56 . 3 . 448–53 . March 1992 . 1368330 . 10.1271/bbb.56.448 .
4. Marcotte EM, Monzingo AF, Ernst SR, Brzezinski R, Robertus JD . X-ray structure of an anti-fungal chitosanase from streptomyces N174 . Nature Structural Biology . 3 . 2 . 155–62 . February 1996 . 8564542 . 10.1038/nsb0296-155 .