| Country: | CHN |
| Type: | G |
| Route: | 221 |
| Map: | G221-路线图.svg |
| Length Km: | 668 |
| Terminus A: | Harbin, Heilongjiang |
| Terminus B: | Tongjiang, Heilongjiang |
| Previous Type: | G |
| Previous Route: | 220 |
| Next Type: | G |
| Next Route: | 222 |
China National Highway 221 (Chinese: 221国道) runs from Harbin to Tongjiang, in Heilongjiang Province. It is 668 kilometres in length and runs northeast from Harbin towards Tongjiang.[1]
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