Chicken ovalbumin upstream promoter-transcription factor explained

Hgncid:7975
Symbol:NR2F1
Altsymbols:ERBAL3, TFCOUP1, EAR-3, COUP-TFI, TCFCOUP1, SVP44
Entrezgene:7025
Omim:132890
Refseq:NM_005654
Uniprot:P10589
Chromosome:5
Arm:q
Band:14
Hgncid:7976
Symbol:NR2F2
Altsymbols:ARP1, TFCOUP2, COUP-TFII, COUPTFB, SVP40
Entrezgene:7026
Omim:107773
Refseq:NM_021005
Uniprot:P24468
Chromosome:15
Arm:q
Band:26

The chicken ovalbumin upstream promoter transcription factor (COUP-TFs) proteins are members of the nuclear receptor family of intracellular transcription factors.[1] There are two variants of the COUP-TFs, labeled as COUP-TFI and COUP-TFII encoded by the and genes respectively.

COUP-TFs play critical roles in the development of organisms.[2]

Notes and References

  1. Qiu Y, Krishnan V, Zeng Z, Gilbert DJ, Copeland NG, Gibson L, Yang-Feng T, Jenkins NA, Tsai MJ, Tsai SY . Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes . Genomics . 29 . 1 . 240–6 . 1995 . 8530078 . 10.1006/geno.1995.1237 . free .
  2. Ming-Jer Tsai . Park JI, Tsai SY, Tsai MJ . Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions . The Keio Journal of Medicine . 52 . 3 . 174–81 . 2003 . 14529150 . 10.2302/kjm.52.174. free .