| Chester A. Mathis | |
| Education: | UC Davis Ph.D. |
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Chester Mathis is an American chemist who is currently the Distinguished Professor of Radiology at University of Pittsburgh and holds the UPMC Endowed Chair of PET Research.[2] [3] [4]
He is known for is work with William E. Klunk on a PET radiotracer for imaging amyloid, a protein linked to neurodegenerative diseases including Alzheimer’s. His efforts led to the creation of a novel category of high-efficacy radiopharmaceutical agents, for example Pittsburgh Compound-B (PiB), which can be used to assess beta-amyloid in the living human brain using PET scanning, and which is a fluorescent analog of thioflavin T. For his work on Alzheimer's disease he has received the Metlife Foundation Award (2004)[5] and the Potamkin Prize (2008).[6]