| Official Name: | Chesapeake, Missouri |
| Settlement Type: | Census-Designated Place |
| Mapsize: | 250x200px |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Missouri |
| Subdivision Type2: | County |
| Subdivision Name2: | Lawrence |
| Unit Pref: | Imperial |
| Area Footnotes: | [1] |
| Area Total Km2: | 1.16 |
| Area Land Km2: | 1.15 |
| Area Water Km2: | 0.00 |
| Area Total Sq Mi: | 0.45 |
| Area Land Sq Mi: | 0.45 |
| Area Water Sq Mi: | 0.00 |
| Population As Of: | 2020 |
| Population Total: | 48 |
| Population Density Km2: | 41.62 |
| Population Density Sq Mi: | 107.87 |
| Blank Name: | FIPS code |
| Blank Info: | 29-13582 |
| Blank1 Name: | GNIS feature ID |
| Blank1 Info: | 2587059 |
Chesapeake is an unincorporated community and census-designated place in Lawrence County, Missouri, United States. It is located on Route 174, approximately five miles east of Mount Vernon.
Chesapeake currently houses a fish hatchery, operated by the Missouri Department of Conservation.
A post office called Chesapeake was established in 1850, and remained in operation until 1914.[2] The community's name commemorates the Capture of USS Chesapeake.[3]