| Cherry Valley Creek | |
| Pushpin Map: | USA New York#USA |
| Pushpin Map Caption: | Location of the mouth of the Cherry Valley Creek in New York State. |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New York |
| Subdivision Type3: | Region |
| Subdivision Name3: | Central New York |
| Subdivision Type4: | County |
| Subdivision Name4: | Otsego |
| Length: | 34.1miles |
| Source1 Location: | Near Cherry Valley |
| Source1 Coordinates: | 42.8325°N -74.7772°W |
| Mouth: | Susquehanna River |
| Mouth Location: | Milford |
| Mouth Coordinates: | 42.5906°N -74.9317°W |
| Tributaries Left: | Pleasant Brook |
| Tributaries Right: | Shellrock Creek, Willow Creek, O' Connell Brook |
Cherry Valley Creek is a 34.1adj=midNaNadj=mid[1] headwater tributary of the Susquehanna River in central New York, United States.
Cherry Valley Creek flows southwesterly through the Cherry Valley in Otsego County, making its way through the towns of Cherry Valley, Roseboom, and Middlefield before joining the Susquehanna River east of the village of Milford.