| Official Name: | Cherokee Pass, Missouri |
| Settlement Type: | Census-designated place |
| Pushpin Map: | Missouri#USA |
| Pushpin Label: | Cherokee Pass |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Missouri |
| Subdivision Type2: | County |
| Subdivision Name2: | Madison |
| Unit Pref: | Imperial |
| Area Footnotes: | [1] |
| Area Total Km2: | 5.42 |
| Area Land Km2: | 5.39 |
| Area Water Km2: | 0.03 |
| Area Total Sq Mi: | 2.09 |
| Area Land Sq Mi: | 2.08 |
| Area Water Sq Mi: | 0.01 |
| Population As Of: | 2020 |
| Population Footnotes: | [2] |
| Population Total: | 271 |
| Population Density Km2: | 50.24 |
| Population Density Sq Mi: | 130.10 |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 978 |
| Coordinates: | 37.4914°N -90.3061°W |
| Postal Code Type: | ZIP code |
| Postal Code: | 63645 (Fredericktown)[3] |
| Area Code: | 573 |
| Blank Name: | GNIS feature ID |
| Blank Info: | 2587058 |
| Blank1 Name: | FIPS Code |
| Blank1 Info: | 29-13474 |
Cherokee Pass is an unincorporated community and census-designated place in Madison County, Missouri, United States. As of the 2020 census, it had a population of 271,[2] up from 235 in 2010.
Cherokee Pass is located on U.S. Route 67 in central Madison County, approximately 5miles south of Fredericktown, the county seat, and north of Silva. The community sits at an elevation of on the height of land between north-flowing tributaries of the Little St. Francis River and south-flowing Twelvemile Creek; both waterways are tributaries of the St. Francis River.
According to the U.S. Census Bureau, the Cherokee Pass CDP has an area of 2.09sqmi, of which 0.01sqmi, or 0.52%, are water.[1]