| Chepigana | |
| Mapsize: | 300px |
| Pushpin Map: | Panama |
| Pushpin Label Position: | right |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location of the district capital in Panama |
| Subdivision Type: | Country |
| Subdivision Name: |  Panama |
| Subdivision Type1: | Province |
| Subdivision Name1: | Darién Province |
| Subdivision Type2: | Capital |
| Subdivision Name2: | La Palma |
| Area Footnotes: | [1] |
| Area Total Km2: | 4625.1 |
| Population As Of: | 2010 Census |
| Population Footnotes: | [2] |
| Population Total: | 30110 |
| Population Blank1 Title: | Ethnicities |
| Timezone: | ETZ |
| Utc Offset: | -5 |
| Coordinates: | 8.41°N -78.15°W |
Chepigana District (pronounced as /es/) is a district (distrito) of Darién Province in Panama. The population according to the 2000 census was 27,461,[3] and had risen to 30,110 in the 2010 census,[2] prior to the creation of Santa Fe District. Since the separation of Santa Fe District, Chepigana covers a total area of .[1] The capital lies at the town of La Palma.[3]
On 14 July 2017, the National Assembly decreed the separation of seven corregimientos from Chepigana District to create Santa Fe District,[4] which took effect in 2018.[5]
Since 2018, Chepigana District has been divided into the following corregimientos: