| Chemilly-sur-Serein | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Chemilly-sur-Serein (Yonne).svg |
| Coordinates: | 47.7719°N 3.8628°W |
| Insee: | 89095 |
| Postal Code: | 89800 |
| Arrondissement: | Auxerre |
| Canton: | Chablis |
| Mayor: | Gérald Vilain[1] |
| Term: | 2020 - 2026 |
| Elevation Min M: | 141 |
| Elevation Max M: | 272 |
| Area Km2: | 13.00 |
Chemilly-sur-Serein (in French pronounced as /ʃəmiji syʁ səʁɛ̃/, literally Chemilly on Serein) is a commune in the Yonne department in Bourgogne-Franche-Comté in north-central France.