| Cheektowaga High School | |
| Streetaddress: | 3600 Union Road |
| City: | Cheektowaga |
| State: | New York |
| County: | Erie |
| Zipcode: | 14225 |
| Coordinates: | 42.911°N -78.757°W |
| Principal: | Karin Cyganovich |
| Head: | Micah D. Hanford Joshua Strzelec |
| Head Label: | Assistant Principals |
| Teaching Staff: | 52.00 (FTE) |
| Ratio: | 12.62 |
| Grades: | 9-12 |
| Team Name: | Warriors |
| Yearbook: | Centorial |
| Enrollment: | 686 (2018-19)[1] |
| Free Label: | Athletic Director Dean of Students |
| Free Text: | Brian J. Hickson |
| Homepage: | Cheektowaga High School |
Cheektowaga Central High School is a high school in Cheektowaga, New York located at 3600 Union Road and serves grades 9 through 12. The current principal is Karin Cyganovich and the current assistant principals are Mr. Micah Hanford and Mr. Joshua Strzelec. It is part of the Cheektowaga Central School District.
The first secondary school in Cheektowaga was Pine Hill High School, erected in 1921 at 1635 East Delavan Avenue. This school operated for forty years before the current Cheektowaga Central High School was constructed and opened in 1960. The high school housed grades 7-12, until the opening of Cheektowaga Central Middle School in 2003.