| Chauffailles | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason Chauffailles.svg |
| Insee: | 71120 |
| Postal Code: | 71170 |
| Arrondissement: | Charolles |
| Canton: | Chauffailles |
| Mayor: | Stéphanie Dumoulin[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | La Clayette Chauffailles en Brionnais |
| Coordinates: | 46.2072°N 4.3408°W |
| Elevation M: | 440 |
| Elevation Min M: | 352 |
| Elevation Max M: | 653 |
| Area Km2: | 22.63 |
Chauffailles (pronounced as /fr/) is a commune in the Saône-et-Loire department in the region of Bourgogne-Franche-Comté in eastern France.
Chaufailles lies in the extreme south of the department of Saône-et-Loire at the foot of the Beaujolais mountains.
Chauffailles was the base of the Congrégation des Soeurs de l'Enfant-Jésus de Chauffailles, an order of teaching nuns founded by Reine Antier (1801–83).