| Charmes-la-Grande | |
| Commune Status: | Commune |
| Arrondissement: | Saint-Dizier |
| Canton: | Joinville |
| Insee: | 52110 |
| Postal Code: | 52110 |
| Mayor: | Gilbert Humbert[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | CC Bassin de Joinville en Champagne |
| Coordinates: | 48.3847°N 4.9942°W |
| Elevation M: | 220 |
| Elevation Min M: | 209 |
| Elevation Max M: | 321 |
| Area Km2: | 11.43 |
Charmes-la-Grande (in French pronounced as /ʃaʁm la ɡʁɑ̃d/) is a commune in the Haute-Marne department in north-eastern France.