Charlotte Deane Explained

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Charlotte Mary Deane (born 1975) is an English Professor of Structural Bioinformatics and the former Head of the Department of Statistics at the University of Oxford. Deane was appointed as Executive Chair of the Engineering and Physical Sciences Research Council (EPSRC) on 16 November 2023.[1]

Early life and education

Charlotte Deane was born in May 1975.[2] She completed her undergraduate education at University College, Oxford studying chemistry, completing her final year project in Graham Richards' group. She then went to the University of Cambridge to study structural bioinformatics supervised by Tom Blundell.[3] In 2000 she published her thesis entitled "Protein structure prediction: amino acid propensities and comparative modelling".[4]

Career and research

Deane moved to UCLA where she stayed for two years supervised by David Eisenberg as a Wellcome Trust Research Fellow, before moving back to Oxford.[5]

Her research is focused on the prediction of protein structures, particularly antibodies. Her research group, Oxford Protein Informatics Group (OPIG), created a database of antibody structures called SABDab[6] and a server for prediction of antibody structures called SAbPred.[7] [8] [9]

In addition, Deane's research is focused on immunoinformatics, biological networks and small molecules.[10]

Honours and awards

In 2007 and 2008, Deane was awarded an Oxford Teaching Award.[11] [12] In 2002 she was elected as fellow of Kellogg College and University Lecturer.[13] In 2010 she was elected as Professor of Structural Bioinformatics and in October 2015 she was appointed Head of the Department of Statistics at the University of Oxford.[14] [15] She is the first female Head of department since the department was created in 1988.

In 2014, Deane became Associate Head of the Mathematical Physical and Life Sciences (MPLS) division and the Deputy Head of the Division in 2018.[16] [17]

Deane became a fellow of St Anne's College in 2015.[18]

In September 2019, Deane was appointed Deputy Executive Chair of the Engineering and Physical Sciences Research Council (EPSRC).[19]

As of January 2022, Deane joined Exscientia as Chief Scientist of Biologics AI.[20]

She was appointed Member of the Order of the British Empire (MBE) in the 2022 Birthday Honours for services to Covid-19 research.

Notes and References

  1. Web site: 2023-11-16 . New Executive Chair of EPSRC named . 2024-04-25 . www.ukri.org . en-GB.
  2. Web site: Charlotte Deane. https://web.archive.org/web/20010503111925/http://www-cryst.bioc.cam.ac.uk/~charlotte/cv1.html. dead. 2001-05-03. 2001-05-03. 2018-02-17.
  3. Web site: Charlotte Deane 2020 Science. 2020science.net. en. 2018-02-17.
  4. Web site: Thesis. Deane. Charlotte. idiscover.lib.cam.ac.uk. en. 2018-02-17.
  5. Web site: Former Lab Members David Eisenberg's Lab. eisenberglab.mbi.ucla.edu. en-US. 2018-02-17.
  6. Web site: SAbDab - Structural Antibody Database. opig.stats.ox.ac.uk. en.
  7. Web site: SAbPred - Structural Antibody Prediction Server. opig.stats.ox.ac.uk. en. 2018-02-17. 2019-07-17. https://web.archive.org/web/20190717142340/http://opig.stats.ox.ac.uk/webapps/sabdab-sabpred/WelcomeSAbPred.php. dead.
  8. Dunbar. James. Krawczyk. Konrad. Leem. Jinwoo. Baker. Terry. Fuchs. Angelika. Georges. Guy. Shi. Jiye. Deane. Charlotte M.. 2014-01-01. SAbDab: the structural antibody database. Nucleic Acids Research. en. 42. D1. D1140–D1146. 10.1093/nar/gkt1043. 24214988. 0305-1048. 3965125.
  9. Dunbar. James. Krawczyk. Konrad. Leem. Jinwoo. Marks. Claire. Nowak. Jaroslaw. Regep. Cristian. Georges. Guy. Kelm. Sebastian. Popovic. Bojana. 2016-07-08. SAbPred: a structure-based antibody prediction server. Nucleic Acids Research. en. 44. W1. W474–W478. 10.1093/nar/gkw361. 27131379. 0305-1048. 4987913.
  10. Web site: Charlotte Deane - Research Interests. Charlotte Deane.
  11. News: Oxford Teaching Awards 2007–2008. 2008-10-22. GAZETTE. 2018-02-17. https://web.archive.org/web/20180224220858/https://www.ox.ac.uk/gazette/2008-9/supps/1_4857.pdf. 2018-02-24. dead.
  12. News: Oxford Teaching Awards 2006–2007. 2007-11-28. GAZETTE. 2018-02-17. https://web.archive.org/web/20180224221210/https://www.ox.ac.uk/gazette/2007-8/supps/1_4826.pdf. 2018-02-24. dead.
  13. Web site: Oxf. Univ. Gazette, 26 September 2002: Examinations and Boards. ox.ac.uk. 2018-02-17. https://web.archive.org/web/20180227104727/https://www.ox.ac.uk/gazette/2002-3/weekly/260902/exam.htm. 27 February 2018. dead.
  14. Web site: Notices, Oxford University Gazette. Oxford. University of. ox.ac.uk. en. 2018-02-17. https://web.archive.org/web/20151222093459/https://www.ox.ac.uk/gazette/2015-2016/1october2015-no5107/notices/. 2015-12-22. dead.
  15. Web site: Congratulations to Prof Charlotte Deane taking over as Head of Dept today. . Statistics. Oxford. 1 Oct 2015. @oxfordstats. en. 2018-02-17.
  16. Web site: Charlotte Deane - Positions and Employment. Charlotte Deane.
  17. Web site: MPLS Awards Announced by Charlotte Deane, Deputy Head of Division.
  18. Web site: St Anne's Fellows. 2015. St Anne's College. 2019-08-29. 2016-10-24. https://web.archive.org/web/20161024095258/http://www.st-annes.ox.ac.uk/fileadmin/documents/Publications/The_Ship_2016_LOW_RES.pdf. dead.
  19. Web site: EPSRC appoints Professor Charlotte Deane as Deputy Executive Chair — Mathematical, Physical and Life Sciences Division. www.mpls.ox.ac.uk. 2019-09-11.
  20. Web site: 2022-01-19. Professor Charlotte Deane Joins Exscientia as Chief Scientist of Biologics AI. 2022-01-27. Exscientia.

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