| Honorific-Prefix: | Jonkheer |
| Charles de Brouckère | |
| Office: | Mayor of Brussels |
| Term Start: | 5 October 1848 |
| Term End: | 20 April 1860[1] |
| Predecessor: | François-Jean Wyns de Raucour |
| Successor: | André-Napoléon Fontainas |
| Birth Name: | Charles Joseph Marie Ghislain de Brouckère |
| Birth Date: | 1796 1, df=yes |
| Birth Place: | Bruges, Austrian Netherlands |
| Death Place: | Brussels, Belgium |
| Nationality: | Belgian |
| Party: | Liberal Party |
| Occupation: | Politician, nobleman |
Jonkheer Charles Joseph Marie Ghislain de Brouckère (pronounced as /fr/; 18 January 1796 – 20 April 1860) was a Belgian nobleman, liberal politician and mayor of the City of Brussels.
Born in Bruges, elder brother of future Prime Minister of Belgium Henri de Brouckère, Charles entered politics in the period when modern Belgium formed the southern part of the United Kingdom of the Netherlands. He worked as a banker in Maastricht and served as a representative for the province of Limburg in the Second Chamber of parliament.
During the Belgian Revolution of 1830, De Brouckère was a member of the francophile and francophone party, which favoured annexation by France. In the newly independent Belgium, he served as Finance Minister, Interior Minister, and War Minister, for short periods in 1831. He taught as a professor at the Free University of Brussels, and in 1848 became burgomaster of Brussels, a post he held continuously until his death. He is interred at Brussels Cemetery.
De Brouckère was responsible for major urban renewal in Brussels, including the creation of water mains, as well as the first boulevards in the city. Today, the Place de Brouckère/De Brouckèreplein, and De Brouckère metro station, in central Brussels, are named after him.