| Caption: | Portrait by Gilbert Stuart |
| Constituency Mp: | Hillsborough |
| Parliament: | Parliament of IrelandIrish |
| Term Start: | 1771 |
| Term End: | 1776 |
| Constituency Mp1: | County Monaghan |
| Parliament1: | Parliament of IrelandIrish |
| Term Start1: | 1783 |
| Term End1: | 1800 |
| Birth Date: | 1731 |
| Death Date: | August 1800 |
| Children: | 12, including Charles and John |
| Charles Leslie | |
| Spouse: | Hon. Prudence Hill-Trevor |
| Parents: | Robert Leslie Frances Ludlow |
Charles Powell Leslie (1731–1800), of Castle Leslie, Glaslough, County Monaghan, was an Irish landowner and politician. He was member of the Irish Parliament for Hillsborough (1771–1776) and County Monaghan (1783–1800).
He was the son of Robert Leslie and Frances (née Rogerson), daughter of Sir John Rogerson, Lord Chief Justice of Ireland, and Elizabeth Ludlow, niece of the regicide Edmund Ludlow.[1] His grandfather was Rev. Charles Leslie.
In 1765, Leslie married Prudence Penelope, daughter of Arthur Hill-Trevor, 1st Viscount Dungannon and Anne Stafford. His children from this marriage included Charles Powell Leslie and Rev. John Leslie. In 1785, he married Mary Anne (née Tench) with whom he had one son and four daughters.[2]