| Charles Preston Wickham | |
| State: | Ohio |
| Term Start: | March 4, 1887 |
| Term End: | March 3, 1891 |
| Preceded: | Charles H. Grosvenor |
| Succeeded: | James W. Owens |
| Party: | Republican |
| Birth Date: | 15 September 1836 |
| Birth Place: | Norwalk, Ohio, US |
| Death Place: | Norwalk, Ohio, US |
| Restingplace: | Woodlawn Cemetery |
| Alma Mater: | Cincinnati Law School |
| Allegiance: |  United States |
| Branch: | Union Army |
| Unit: | 55th Ohio Infantry |
| Serviceyears: | 1861-1865 |
| Rank: | Brevet Lieutenant colonel |
| Battles: | American Civil War |
Charles Preston Wickham (September 15, 1836 – March 18, 1925) was a 19th-century congressman and judge from Norwalk, Huron County, Ohio.
Wickham was born September 15, 1836, in Norwalk, Ohio. He attended the public schools, followed by the Norwalk Academy. He then attended the Cincinnati Law School.
During the American Civil War, he enlisted as a private in Company D, Fifty-fifth Regiment, Ohio Volunteers, in September 1861 and rose to the rank of lieutenant colonel by brevet. He was mustered out of the service July 11, 1865.
Wickham was admitted to the bar in 1858 and practiced in Norwalk. After the Civil War, he resumed the practice of law in Norwalk. He served as prosecuting attorney from 1866 to 1870 and was elected judge of the Court of Common Pleas of the fourth judicial district in 1880 and 1885.
Wickham was then elected as a Republican to the Fiftieth and Fifty-first Congresses (March 4, 1887 – March 3, 1891) and served as chairman of the Committee on Coinage, Weights, and Measures (Fifty-first Congress).
He died in Norwalk, Ohio on March 18, 1925, after being struck by a motorist and was interred in Woodlawn Cemetery.