| Honorific-Prefix: | Most Reverend |
| Charles Impellizzeri | |
| Bishop of Mazara del Vallo | |
| Church: | Catholic Church |
| Diocese: | Diocese of Mazara del Vallo |
| Term: | 1650–1656 |
| Predecessor: | Diego Requeséns |
| Successor: | Juan Lozano (bishop) |
| Consecration: | 8 January 1651 |
| Death Date: | 1656 |
| Nationality: | Italian |
Charles Impellizzeri (died 1656) was a Roman Catholic prelate who served as Bishop of Mazara del Vallo (1650–1656).[1]
On 19 December 1650, Charles Impellizzeri was appointed during the papacy of Pope Innocent X as Bishop of Mazara del Vallo. On 8 January 1651, he was consecrated bishop. He served as Bishop of Mazara del Vallo until his death on 1656.