| Charles Griffin | |
| Birth Name: | Charles Hudson Griffin |
| Birth Date: | 9 May 1926 |
| Birth Place: | Utica, Mississippi, U.S. |
| Death Place: | Utica, Mississippi, U.S. |
| Office1: | Member of the U.S. House of Representatives from Mississippi's 3rd District |
| Term Start1: | March 12, 1968 |
| Term End1: | January 3, 1973 |
| Predecessor1: | John Bell Williams |
| Successor1: | Thad Cochran (Redistricting) |
| Relations: | Isaac Griffin (great-great-grandfather) |
| Alma Mater: | Mississippi State University |
| Battles: | World War II |
Charles Hudson Griffin (May 9, 1926 - September 10, 1989) was an American World War II veteran and politician who served as a member of the United States House of Representatives from Mississippi's 3rd congressional district from 1968 to 1973.
Griffin was born on a farm near Utica, Mississippi. He attended Utica High School and Hinds Community College before graduating from Mississippi State University in 1949. Griffin was the great-great-grandson of Isaac Griffin, a Congressman from Pennsylvania.
He served in the United States Navy from 1944 to 1946 in Pacific War as a third class apprentice seaman and quartermaster.
Griffin served as assistant to United States Representative John Bell Williams from July 1, 1949, to January 15, 1968.
Griffin was elected as a Democrat to the Ninetieth Congress in a special election triggered by Williams' successful bid for governor of Mississippi. He was reelected to the two succeeding Congresses (March 12, 1968 - January 3, 1973). He was not a candidate for reelection to the Ninety-third Congress in 1972.
He then served as the Secretary of the Mississippi State senate from 1980 to 1989.
He was a resident of Utica, Mississippi, until his death there on September 10, 1989.