| Charles Jérémie Coulombe | |
| Constituency Mp: | Maskinongé |
| Parliament: | Canadian |
| Predecessor: | Alexis Lesieur Desaulniers |
| Successor: | Joseph-Hormisdas Legris |
| Term Start: | 1887 |
| Term End: | 1891 |
| Birth Date: | 23 October 1846 |
| Birth Place: | St-Cuthbert, Canada East |
| Death Place: | L'Assomption, Quebec, Canada |
| Nationality: | Canadian |
| Party: | Conservative |
| Occupation: | physician |
Charles-Jérémie Coulombe (October 23, 1846 - December 1, 1938) was a physician and political figure in Quebec. He represented Maskinongé in the House of Commons of Canada from 1887 to 1891 as a Conservative member.
He was born in St-Cuthbert, Canada East, and educated at the college in L'Assomption. In 1879, he married Marie Noémi Bernier. He served as a major in the militia. Coulombe was an unsuccessful candidate for a seat in the House of Commons in 1884. His attempts at reelection in 1891 and 1896 were unsuccessful.