| Chapelle-Guillaume | |
| Commune Status: | Commune |
| Arrondissement: | Nogent-le-Rotrou |
| Canton: | Brou |
| Insee: | 28078 |
| Postal Code: | 28330 |
| Mayor: | Joël Ferré[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 48.1139°N 0.9058°W |
| Elevation M: | 207 |
| Elevation Min M: | 184 |
| Elevation Max M: | 251 |
| Area Km2: | 19.86 |
Chapelle-Guillaume (in French pronounced as /ʃapɛl ɡijom/) is a commune in the Eure-et-Loir department in northern France.