Vachellia rigidula explained

Vachellia rigidula, commonly known as blackbrush acacia or chaparro prieto, and also known as Acacia rigidula, is a species of shrub or small tree in the legume family, Fabaceae. Its native range stretches from Texas in the United States south to central Mexico. This perennial is not listed as being threatened.[1] It reaches a height of 5feet-15feetft (-ft).[2] Blackbrush acacia grows on limestone hillsides and canyons.[3]

Phytochemistry

A phytochemical study of V. rigidula[4] by workers at the Texas A & M University Agricultural Research and Extension Center at Uvalde, TX, reported the presence of over forty alkaloids, including low amounts (up to around 15 ppm) of several phenolic amines that had previously been found by the same research group in the related species Senegalia berlandieri,[5] but which otherwise are known only as products of laboratory synthesis. Compounds found in the highest concentrations (ranging from a few hundred to a few thousand ppm) were phenethylamine, tryptamine, tyramine, and β-Methylphenethylamine (that it can be misidentified as amphetamine).[6] Other notable compounds reported were N,N-dimethyltryptamine, mescaline, and nicotine, although these were found in low concentrations (e.g. mescaline at 3-28 ppm).

The presence of such an unprecedented chemical range of psychoactive compounds, including ones not previously found in nature, in a single plant species has led to the suggestion that some of these findings may have resulted from cross-contamination or were possibly artifacts of the analytical technique.[7]

Uses

Vachellia rigidula is used in weight loss dietary supplements because of the presence of chemical compounds claimed to stimulate beta-receptors to increase lipolysis and metabolic rate and decrease appetite.[8]

Vachellia rigidula is also known as a large honey producer and early blooming plant for its native region.[2]

Safety

In 2015, 52% of supplements labeled as containing Acacia rigidula were found to be adulterated with synthetic BMPEA, an amphetamine isomer.[9] Consumers following recommended maximum daily servings would consume a maximum of 94 mg of BMPEA per day.[9] In 2012, however, the FDA determined that BMPEA was not naturally present in Acacia rigidula leaves.[10]

External links

Notes and References

  1. Web site: Acacia rigidula. LegumeWeb. International Legume Database & Information Service (ILDIS). 2019-10-18. live. https://web.archive.org/web/20070629102904/http://www.ildis.org/LegumeWeb?version~10.01&LegumeWeb&tno~7639&genus~Acacia&species~rigidula. June 29, 2007.
  2. Web site: Acacia rigidula Benth . Native Plant Database . Lady Bird Johnson Wildflower Center . 2009-06-30.
  3. Web site: Blackbrush Acacia, Chaparro Prieto, Catclaw, Gavia . Texas Native Plants Database . . 2009-06-30.
  4. 10.1016/S0031-9422(97)01022-4 . Toxic amines and alkaloids from acacia rigidula . Phytochemistry . 49 . 5 . 1377–80 . 1998 . Clement . Beverly A . Goff . Christina M . Forbes . T.David A .
  5. 10.1016/S0031-9422(97)00240-9 . Toxic amines and alkaloids from Acacia berlandieri . Phytochemistry . 46 . 2 . 249–54 . 1997 . Clement . Beverly A. . Goff . Christina M. . Forbes . T. David A. .
  6. Pawar . RS . Grundel . E . Fardin-Kia . AR . Rader . JI . Determination of selected biogenic amines in Acacia rigidula plant materials and dietary supplements using LC-MS/MS methods. . Journal of Pharmaceutical and Biomedical Analysis . January 2014 . 88 . 457–66 . 10.1016/j.jpba.2013.09.012 . 24176750.
  7. Web site: Acacias and Natural Amphetamine . Ask Dr. Shulgin Online . Center for Cognitive Liberty & Ethics . 2001-09-26.
  8. WO . 2006099274 . application . Dietary Supplement and Method of Using Same . 2006-09-14 . 2006-03-13 . Jared R. Wheat.
  9. 10.1002/dta.1793 . An amphetamine isomer whose efficacy and safety in humans has never been studied, β-methylphenylethylamine (BMPEA), is found in multiple dietary supplements . Drug Testing and Analysis . 328–33. 2015 . Cohen . Pieter A. . Bloszies . Clayton . Yee . Caleb . Gerona . Roy . 25847603 . 8. 3–4 . free .
  10. Web site: Untested Stimulant Still in Dietary Supplements. Brenda . Goodman. WebMD. 2015-04-07.