| Chêne-en-Semine | |
| Commune Status: | Commune |
| Arrondissement: | Saint-Julien-en-Genevois |
| Canton: | Saint-Julien-en-Genevois |
| Insee: | 74068 |
| Postal Code: | 74270 |
| Mayor: | Paul Rannard[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | CC Usses et Rhône |
| Coordinates: | 46.0475°N 5.8594°W |
| Elevation Min M: | 320 |
| Elevation Max M: | 553 |
| Area Km2: | 9.46 |
Chêne-en-Semine (in French pronounced as /ʃɛn ɑ̃ səmin/; Châno-en-Semena) is a commune in the Haute-Savoie department in the Auvergne-Rhône-Alpes region in south-eastern France.