Cetrimide Explained

Cetrimide, or alkyltrimethylammonium bromide, is an antiseptic which is a mixture of three quaternary ammonium compounds: tetradonium bromide (TTAB or MITMAB), cetrimonium bromide (CTAB), and laurtrimonium bromide (DTAB or LTAB).[1] It was first discovered and developed by ICI and introduced under the brand name Cetavlon.[2] It is used as a 1-3 % solution for cleaning roadside accident wounds.[3] ICI also introduced Savlon, which was a combination of cetrimide and chlorhexidine. ICI later sold the Savlon brand OTC to Johnson & Johnson in May 1992.[4] Cetrimide is used in various applications such as antiseptic agents, diagnostic test and analysis, topical formulations, and dental treatment.[5]

Notes and References

  1. Book: Council of Europe . Council of Europe . European Pharmacopoeia (Ph. Eur.) . . Strasbourg . 2007 . 6.0 . 978-92-871-6054-6 . 170932841 . 1484–5 .
  2. Web site: Newspaper Article - Page 11 Advertisements Column 1 . 2013-08-15 . https://web.archive.org/web/20131005011321/http://newspapers.nl.sg/Digitised/Article/straitstimes19721231.2.68.1.aspx# . 2013-10-05 . dead .
  3. Book: Essentials of Medical Pharmacology . 7th . KD . Tripathi . 900.
  4. Web site: JOHNSON & JOHNSON ACQUIRES SAVLON OTC BRANDS FROM ICI - Free Online Library. dead . https://web.archive.org/web/20131005000541/http://www.thefreelibrary.com/JOHNSON+%26+JOHNSON+ACQUIRES+SAVLON+OTC+BRANDS+FROM+ICI-a012169404 . 2013-10-05 .
  5. Web site: 22 October 2021. Cetrimide Applications. live. https://web.archive.org/web/20190405092704/https://novonordiskpharmatech.com/products/cetrimide/ . 2019-04-05 .

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