Cetirizine/pseudoephedrine explained

Cetirizine/pseudoephedrine (Zyrtec-D) is an antihistamine and decongestant formulation. It is a fixed-dose combination drug containing 5 mg cetirizine hydrochloride and 120 mg pseudoephedrine hydrochloride for symptoms related to seasonal allergic rhinitis.^{[1] [2] [3]} Cetirizine/pseudoephedrine gained approval from the U.S. Food and Drug Administration in 2001 as a prescription drug and became over-the-counter (OTC) in 2007.^[4]

Notes and References

1. Web site: ZYRTEC-D ALLERGY PLUS CONGESTION- cetirizine hydrochloride and pseudoephedrine hydrochloride tablet, film coated, extended release . DailyMed . 25 April 2022 . 28 September 2022.
2. Badorrek P, Dick M, Schauerte A, Hecker H, Murdoch R, Luettig B, Hohlfeld JM, Krug N . 6 . A combination of cetirizine and pseudoephedrine has therapeutic benefits when compared to single drug treatment in allergic rhinitis . International Journal of Clinical Pharmacology and Therapeutics . 47 . 2 . 71–77 . February 2009 . 19203562 . 10.5414/cpp47071 . Dustri-Verlgag Dr. Karl Feistle .
3. Grosclaude M, Mees K, Pinelli ME, Lucas M, Van de Venne H . Cetirizine and pseudoephedrine retard, given alone or in combination, in patients with seasonal allergic rhinitis . Rhinology . 35 . 2 . 67–73 . June 1997 . 9299654 . 10.1.1.500.9540 .
4. Web site: FDA approves J&J’s non-prescription Zyrtec-D . PharmaTimes . 12 November 2007 . 12 December 2022.