CDR2 (gene) explained

Cerebellar degeneration-related protein 2 is a protein that in humans is encoded by the CDR2 gene.^{[1] [2]}

See also

• Cerebellar degeneration-related protein 1

Further reading

• Gress T, Baldini A, Rocchi M . In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1. . Genomics . 13 . 4 . 1340–2 . 1992 . 1505970 . 10.1016/0888-7543(92)90063-X . etal.
• Sakai K, Mitchell DJ, Tsukamoto T, Steinman L . Isolation of a complementary DNA clone encoding an autoantigen recognized by an anti-neuronal cell antibody from a patient with paraneoplastic cerebellar degeneration. . Ann. Neurol. . 30 . 5 . 738 . 1992 . 1763903 . 10.1002/ana.410300523 . free .
• Sakai K, Mitchell DJ, Tsukamoto T, Steinman L . Isolation of a complementary DNA clone encoding an autoantigen recognized by an anti-neuronal cell antibody from a patient with paraneoplastic cerebellar degeneration. . Ann. Neurol. . 28 . 5 . 692–8 . 1991 . 2260856 . 10.1002/ana.410280515 . 28532317 .
• Bonaldo MF, Lennon G, Soares MB . Normalization and subtraction: two approaches to facilitate gene discovery. . Genome Res. . 6 . 9 . 791–806 . 1997 . 8889548 . 10.1101/gr.6.9.791 . free .
• Fletcher CF, Okano HJ, Gilbert DJ . Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens. . Genomics . 45 . 2 . 313–9 . 1998 . 9344654 . 10.1006/geno.1997.4925 . etal.
• Takanaga H, Mukai H, Shibata H . PKN interacts with a paraneoplastic cerebellar degeneration-associated antigen, which is a potential transcription factor. . Exp. Cell Res. . 241 . 2 . 363–72 . 1998 . 9637778 . 10.1006/excr.1998.4060 . etal.
• Okano HJ, Park WY, Corradi JP, Darnell RB . The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival. . Genes Dev. . 13 . 16 . 2087–97 . 1999 . 10465786 . 10.1101/gad.13.16.2087 . 316965 .
• Sakai K, Shirakawa T, Li Y . Interaction of a paraneoplastic cerebellar degeneration-associated neuronal protein with the nuclear helix-loop-helix leucine zipper protein MRG X. . Mol. Cell. Neurosci. . 19 . 4 . 477–84 . 2002 . 11988016 . 10.1006/mcne.2001.1059 . 26659745 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Sutton IJ, Steele J, Savage CO . An interferon-gamma ELISPOT and immunohistochemical investigation of cytotoxic T lymphocyte-mediated tumour immunity in patients with paraneoplastic cerebellar degeneration and anti-Yo antibodies. . J. Neuroimmunol. . 150 . 1–2 . 98–106 . 2004 . 15081253 . 10.1016/j.jneuroim.2003.12.026 . 45697226 . etal.
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Balbo M, Barel M, Lottin-Divoux S . Infection of human B lymphoma cells by Mycoplasma fermentans induces interaction of its elongation factor with the intracytoplasmic domain of Epstein-Barr virus receptor (gp140, EBV/C3dR, CR2, CD21). . FEMS Microbiol. Lett. . 249 . 2 . 359–66 . 2005 . 16054780 . 10.1016/j.femsle.2005.06.052 . etal. free .

Notes and References

1. Fathallah-Shaykh H, Wolf S, Wong E, Posner JB, Furneaux HM . Cloning of a leucine-zipper protein recognized by the sera of patients with antibody-associated paraneoplastic cerebellar degeneration . Proc Natl Acad Sci U S A . 88 . 8 . 3451–4 . May 1991 . 2014264 . 51465 . 10.1073/pnas.88.8.3451 . 1991PNAS...88.3451F . free .
2. Web site: Entrez Gene: CDR2 cerebellar degeneration-related protein 2, 62kDa.