Cer6 (retrotransposon) explained

Cer6 is a LTR retrotransposon that is described from sequencing data in the chromosome III of C. elegans.^{[1] [2] [3]}

LTR retrotransposons

LTR retrotransposons are class I transposable element characterized by the presence of long terminal repeats (LTRs) directly flanking an internal coding region. As retrotransposons, they mobilize through reverse transcription of their mRNA and integration of the newly created cDNA into another location. Their mechanism of retrotransposition is shared with retroviruses, with the difference that most LTR-retrotransposons do not form infectious particles that leave the cells and therefore only replicate inside their genome of origin.

Further reading

• Book: Snyder . L. . Champness . W. . Ch. 9: Transposition and site-specific recombination . Molecular Genetics of Bacteria . ASM Press . Washington DC . 2003 . 1-55581-204-X . 303–340 . 2nd . https://archive.org/details/moleculargenetic0000snyd/page/303 .
• Web site: Bibliography: Transposons as a genetic tool . Citizendium.org .
• Web site: R.A. . Martienssen . P.S. . Springer . Enhancer and Gene Trap Transposon Mutagenesis in Arabidopsis . Cold Spring Harbor Laboratory .

Notes and References

1. Genomic Analysis of Caenorhabditis elegans Reveals Ancient Families of Retroviral-like Elements . Nathan J. Bowen . John F. McDonald . 10.1101/gr.9.10.924 . Genome Res. . 1999 . 9 . 10 . 924–935 . Cold Spring Harbor Laboratory Press . 10523521 . free .
2. Drosophila euchromatic LTR retrotransposons are much younger than the host species in which they reside . N J Bowen . J F McDonald . Genome Res. . 2001 . 11 . 9 . 1527–40 . 10.1101/gr.164201 . 11544196 . 311128 .
3. Evolutionary History of Cer Elements and Their Impact on the C. elegans Genome . Eric W. Ganko . Kevin T. Fielman . John F. McDonald . Genome Res. . 2001 . 11 . 12 . 2066–2074 . 10.1101/gr.196201 . 311226 . 11731497 .