Cephalodiscus gilchristi explained

Cephalodiscus gilchristi is a sessile hemichordate belonging to the order Cephalodiscida.^[1] It is found in South Africa in 1908.

Parasites

The parasitic copepod Zanclopus cephalodisci has been found in the intestines of Cephalodiscus gilchristi.^[2]

Isolated molecules

Cephalostatin-1,^[3] is a steroidic 13-ringed pyrazine with the empirical formula C₅₄H₇₄N₂O₁₀ that was isolated from Cephalodiscus gilchristi. It is a potent anti-cancer agent that causes cell death in the subnanomolar to picomolar ranges via an atypical apoptosis pathway.^[4]

Notes and References

1. Swalla, B.J. . van der Land, J. . 2020 . Cephalodiscus gilchristi . 266749 . September 17, 2020 . Hemichordata World Database.
2. Maletz, Jörg. (2017) Graptolite Paleobiology. Wiley-Blackwell.
3. Web site: CID 183413 . . May 12, 2012 . en.
4. Nawasreh . Mansour M. . Alzyoud . Elham I. . Al-Mazaydeh . Zainab A. . Rammaha . Majdoleen S. . Yasin . Salem R. . Tahtamouni . Lubna H. . Biological activity and apoptotic signaling pathway of C11-functionalized cephalostatin 1 analogues . Steroids . June 2020 . 158 . 108602 . 10.1016/j.steroids.2020.108602 . 32092307 .