| Central Development Region | |
| Native Name: | Madhyamānchal Bikās Kshetra |
| Mapsize: | 450px |
| Type: | Former region |
| Subdivision Type: | Country |
| Subdivision Name: |  Nepal |
| Subdivision Type1: | Region |
| Seat Type: | Headquarters |
| Seat: | Hetauda, Makwanpur District, Bagmati Province |
| Area Total Km2: | 27,410 |
| Timezone1: | NPT |
| Utc Offset1: | +5:45 |
The Central Development Region (Nepali: मध्यमाञ्चल विकास क्षेत्र, Madhyamānchal Bikās Kshetra) was one of Nepal's five development regions. It was located in the east-central part of the country consisting of the capital city Kathmandu, along with its headquarters at Hetauda.
Before the adoption of provinces in 2015, it comprised three zones: