The Central PA Vipers were a team of the Independent Women's Football League. Based in the Steelton suburb of Harrisburg, Pennsylvania, the Vipers played their home games at Steelton-Highspire School District's War Veterans Memorial Field, also known as Cottage Hill. Prior to playing in the IWFL, the Vipers were a member of the National Women's Football Association in 2006 and 2007 (in their inaugural season, they were called the Harrisburg Angels).
After four seasons and twenty-seven attempts (not counting two forfeits by the Richmond Spirit in 2007), the Vipers finally picked up their first victory on the gridiron on June 6, 2009 thanks to a 48-0 triumph over the Holyoke Hurricanes. The following week, the Vipers continued their string of success, defeating the Cape Fear Thunder, 30-6.
|-| colspan="6" align="center" | Harrisburg Angels (NWFA)|-|2006 || 0 || 8 || 0 || 4th Northern North Atlantic || --|-| colspan="6" align="center" | Central PA Vipers (NWFA)|-|2007 || 2 || 7 || 0 || 4th Northern Central || --|-| colspan="6" align="center" | Central PA Vipers (IWFL)|-|2008 || 0 || 8 || 0 || 6th Eastern North Atlantic || |-|2009 || 2 || 6 || 0 || 18th IWFL2 || --|-!Totals || 4 || 29 || 0|colspan="2"| (including playoffs)
| Date | Opponent | Home/Away | Result | |
|---|---|---|---|---|
| April 18 | New England Intensity | Home | Lost 14-21 | |
| April 25 | Manchester Freedom | Away | Lost 0-47 | |
| May 2 | Erie Illusion | Away | Lost 8-61 | |
| May 9 | Jersey Justice | Away | Lost 0-34 | |
| May 23 | Southern Maine Rebels | Home | Lost 8-14 | |
| June 6 | Holyoke Hurricanes | Home | Won 48-0 | |
| June 13 | Cape Fear Thunder | Home | Won 30-6 | |
| June 20 | Connecticut Crushers | Away | Lost 0-2** |
** = Forfeited