| Central Denkalya | |
| Mapsize: | 200px |
| Mapsize1: | 150px |
| Subdivision Type: | Country |
| Subdivision Type1: | Region |
| Subdivision Name1: | Southern Red Sea |
| Unit Pref: | Metric |
| Timezone: | GMT +3 |
| Utc Offset: | +3 |
Central Denkalya Subregion is a subregion in the Southern Red Sea region (Zoba Debubawi Keyih Bahri) of Eritrea. It is bordered to the northwest by the Are'eta Subregion, to the southeast by the Southern Denkalya Subregion, to the north by the Red Sea, and to the south by Ethiopia.