| Center-Minami Station | |
| Native Name: | センター南駅 |
| Native Name Lang: | ja |
| Type: | station |
| Address: | 1-1 Chigasakichūō, Tsuzuki, Yokohama |
| Borough: | Kanagawa Prefecture |
| Country: | Japan |
| Coordinates: | 35.5455°N 139.5743°W |
| Operator: | Yokohama City Transportation Bureau |
| Platforms: | 2 island platforms |
| Tracks: | 4 |
| Code: | B29 (Blue Line) G04 (Green Line) |
| Map Type: | Japan Yokohama#Japan Kanagawa Prefecture#Japan |
| Map Dot Label: | Center-Minami Station |
is an above-ground metro station located in Tsuzuki-ku, Yokohama, Kanagawa Prefecture, Japan, operated by the Yokohama Municipal Subway. It is an interchange station for the Green Line and Blue Line (Line 3).
Center-Minami Station is served by the Blue Line and Green Line. It is 36.4 kilometers from the terminus of the Blue Line at Shōnandai Station and 4.8 kilometers from the terminus of the Green Line at .
Center-Minami Station has two elevated island platforms serving four tracks. The ground-level station building is located underneath the tracks and platforms.
Center-Minami Station opened on 18 March 1993, when the Line 3 (later named the Blue Line) was extended from Shin-Yokohama Station to Azamino Station. Platform screen doors were installed in April of 2007. Services on the Green Line started on 30 March 2008.