Centalun Explained

Centalun was developed by Boehringer Ingelheim in 1962[1] and is a psycholeptic drug with hypnotic and sedative effects, via allosteric agonism of the GABAA receptor.[2] It was previously used for sedation in medical procedures such as surgery,[3] orthopedics[4] and gynecology,[5] although it is no longer in clinical use. Despite its history of clinical use, centalun was never incorporated into the CSA and therefore remains unregulated as a drug of abuse.

Notes and References

  1. BE . 618130 . Procédé pour l'obtention d'alkinediols .
  2. Janke W, Glathe H . [Experimental Studies on the Psychic Effect of Sedatives Under Normal and Stress Conditions] . German . Psychologische Forschung . 27 . 377–402 . June 1964 . 14233519 . 10.1007/bf00421338 . 144088161 .
  3. Monecke K . [Pre- and Postoperative Use of Centalun in Surgery] . German . Deutsches Medizinisches Journal . 15 . 470–1 . July 1964 . 14238754 .
  4. Bruckschen E . [Sedative Therapy with Centalun in Orthopedics] . German . Deutsches Medizinisches Journal . 15 . 493–4 . July 1964 . 14243120 .
  5. Gerlach W, Gerlach E . [Experiences with Centalun in Obstetrical and Gynecological Patients] . German . Medizinische Monatsschrift . 18 . 131–3 . March 1964 . 14193290 .

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