Cefoperazone/sulbactam explained

Drug Name:Sulcefozone
Type:combo
Component1:Cefoperazone
Class1:β-Lactam antibiotic
Component2:Sulbactam
Class2:β-Lactamase inhibitor
Tradename:Sulcefozone
Pregnancy Category:C
Legal Us:Discontinued[1]
Legal Status:Rx-only
Drugbank:DB01329
Kegg:D08772

Cefoperazone/sulbactam is a combination drug used as an antibiotic. It is effective for the treatment of urinary tract infections.[2] It contains cefoperazone, a β-lactam antibiotic, and sulbactam, a β-lactamase inhibitor, which helps prevent bacteria from breaking down cefoperazone.[3]

Notes and References

  1. Web site: Cefoperazone . .
  2. Greenberg RN, Reilly PM, Weinandt WJ, Bollinger M, Kennedy DJ . Cefoperazone-sulbactam combination in the treatment of urinary tract infections: efficacy, safety, and effects on coagulation . Clinical Therapeutics . 10 . 1 . 52–6 . 1987 . 3329965 .
  3. Singh GS . Beta-lactams in the new millennium. Part-II: cephems, oxacephems, penams and sulbactam . Mini Reviews in Medicinal Chemistry . 4 . 1 . 93–109 . January 2004 . 14754446 . 10.2174/1389557043487547 .

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