Cefonicid Explained

Cefonicide (or cefonicid) is a cephalosporin antibiotic.^[1]

It has a density of 1.92g/cm³.__TOC__

Synthesis

Injectable semi-synthetic cephalosporin antibiotic related to cefamandole, q.v.

Cefonicid is synthesized conveniently by nucleophilic displacement of the 3-acetoxy moiety of 1 with the appropriately substituted tetrazole thiole 2. The mandelic acid amide C-7 side chain is reminiscent of cefamandole.

See also

• Cefazaflur

Notes and References

1. Saltiel E, Brogden RN . Cefonicid. A review of its antibacterial activity, pharmacological properties and therapeutic use . Drugs . 32 . 3 . 222–59 . September 1986 . 3530703 . 10.2165/00003495-198632030-00002 . 243051006 .