Cefmatilen Explained

Cefmatilen (INN, codenamed S-1090) is an orally-active cephalosporin antibiotic. It was developed in Japan and first described in 1992.

In vitro, cefmatilen is highly active against a variety of Gram-positive and Gram-negative bacteria, including Streptococcus pyogenes and Neisseria gonorrhoeae.^[1]

References

1. Tsuji M, Ishii Y, Ohno A, Miyazaki S, Yamaguchi K . In vitro and in vivo antibacterial activities of S-1090, a new oral cephalosporin . Antimicrob Agents Chemother . 39 . 11 . 2544–51 . November 1995 . 8585742 . 162981 . 10.1128/aac.39.11.2544.

Further reading

• Cazzola M . Novel oral cephalosporins . Expert Opin Investig Drugs . 9 . 2 . 237–46 . February 2000 . 11060674 . 10.1517/13543784.9.2.237. 45932120 .