Ced-5 Explained
Cell death abnormality gene 5 |
Organism: | Caenorhabditis elegans |
Taxid: | 6239 |
Symbol: | CED-5 |
Entrezgene: | 177942 |
Homologene: | 55575 |
Refseqmrna: | NM_069537.7 |
Refseqprotein: | NP_501938.1 |
Uniprot: | G5EEN3 |
Chromosome: | IV |
Entrezchromosome: | NC_003282.8 |
Genloc Start: | 10484110 |
Genloc End: | 10492952 |
CED-5 is an ortholog of the mammalian protein Dock180,which present in the nematode worm C. elegans.,[1] the Drosophila melanogaster ortholog of CED-5 is Myoblast city.[2]
Notes and References
- Wu YC, Horvitz HR . C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180 . Nature . 392 . 6675 . 501–4 . April 1998 . 9548255 . 10.1038/33163 . 1998Natur.392..501W . 205002377 .
- Nolan KM, Barrett K, Lu Y, Hu KQ, Vincent S, Settleman J . Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes . Genes & Development . 12 . 21 . 3337–42 . November 1998 . 9808621 . 10.1101/GAD.12.21.3337 . 317223 .