| Cga: | CAY |
| Cganame: | Cayman Islands Olympic Committee |
| Games: | Commonwealth Games |
| Year: | 2010 |
| Flagcaption: | Flag of the Cayman Islands |
| Location: | Delhi, India |
| Competitors: | 17 |
| Flagbearer: | Opening: Closing: |
| Gold: | 1 |
| Silver: | 0 |
| Bronze: | 0 |
| App Begin Year: | 1978 |
Cayman Islands competed in the 2010 Commonwealth Games held in Delhi, India, from 3 to 14 October 2010. They won their first ever gold medal through Cydonie Mothersille in the 200m athletics for women.
| Medal | width=350px | Name | Sport | Event | Date |
|---|---|---|---|---|---|
| October 12 | |||||