Catherine G Galbraith Explained

Catherine G Galbraith
Nationality:American
Fields:Biophysics
Super-Resolution Microscopy
Academic Advisors:Shu Chien
Richard Skalak
Michael Sheetz
Known For:Cell migration
Super-Resolution Microscopy
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Catherine G Galbraith is an American scientist who is an associate professor of Biomedical Engineering at OHSU and Discovery Engine Investigator at Knight Cancer Institute,[1] known for her work in cell mobility and cell migration as well as super-resolution microscopy. Together with James Galbraith, she heads the Galbraith Lab.[2]

Education

Galbraith studied Bioengineering at the University of Pennsylvania in Philadelphia, PA, USA. After receiving her BSc in 1985, she attended a Master's program in Bioengineering, which she finished in 1987. Subsequently, Galbraith earned her Ph.D. in Bioengineering in 1995 at University of California, San Diego, CA, USA, advised by Prof Dr Shu Chien.[3] [1]

Career and research

For her postgraduate work between 1995 and 2000, Galbraith worked as a postdoctoral researcher with Prof Dr Michael Sheetz at Duke University in Durham, NC, USA, focusing primarily on cell mobility and migration.[4] [5] [6] [7] [8]

Between 2000 and 2013, Galbraith worked at the National Institutes of Health, Bethesda, MD, continuing her work on cell mobility and migration. First as a Research Fellow (2000-2005) and an Independent Senior Researcher (2005-2010) at the National Institute of Dental and Craniofacial Research (NIDCR) and finally as a scientist (2010-2013) at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

Between 2010 and 2012, Galbraith was also, for the first time, a visiting scientist at Howard Hughes Medical Institute's Janelia Research Campus.

Collaborations with scientists at Janelia, in particular Eric Betzig and Harald Hess, resulted, amongst others, in key papers that helped to establish the localization-based super-resolution microscopy technique Photoactivated localization microscopy (PALM).[9] [10] [11] [12] Betzig received the Nobel Prize for PALM in 2014.

Since 2013, Galbraith has been an Associate Professor of Biomedical Engineering at OHSU and Discovery Engine Investigator at Knight Cancer Institute.[1]

Together with her husband, James Galbraith, Galbraith uses multidisciplinary approaches and advanced microscopy techniques to explore the mechanisms behind cellular decision-making in a variety of processes, including motility, synaptogenesis, and metastasis.[13] [14] [15]

Since 2019, Galbraith has also again been a visiting scientist at Howard Hughes Medical Institute's Janelia Research Campus.

Galbraith is a well-known scientist in the field who is frequently invited to speak at conferences, seminars, and workshops.[16] [17]

Awards and honours

Notes and References

  1. Web site: Catherine G. Galbraith Ph.D. | OHSU People | OHSU. www.ohsu.edu. 15 October 2023.
  2. Web site: Home. Galbraith Lab. 15 October 2023.
  3. Web site: About Us. Galbraith Lab. 15 October 2023.
  4. A micromachined device provides a new bend on fibroblast traction forces. Catherine G.. Galbraith. Michael P.. Sheetz. 19 August 1997. Proceedings of the National Academy of Sciences. 94. 17. 9114–9118. 10.1073/pnas.94.17.9114. 9256444. 23061 . 1997PNAS...94.9114G . free .
  5. C.G.. Galbraith. R.. Skalak. S.. Chien. 15 October 1998. Cell Motility and the Cytoskeleton. 40. 4. 317–330. CrossRef. 10.1002/(SICI)1097-0169(1998)40:4<317::AID-CM1>3.0.CO;2-8. 9712262 .
  6. Michael P.. Sheetz. Dan P.. Felsenfeld. Catherine G.. Galbraith. 1 February 1998. Trends in Cell Biology. 8. 2. 51–54. 10.1016/S0962-8924(98)80005-6. 9695809 .
  7. Catherine G. Galbraith. Michael P. Sheetz. 1 October 1998. Current Opinion in Cell Biology. 10. 5. 566–571. 10.1016/S0955-0674(98)80030-6. 9818165 .
  8. Cell migration as a five-step cycle. M. P.. Sheetz. D.. Felsenfeld. C. G.. Galbraith. D.. Choquet. 15 October 1999. Biochemical Society Symposium. 65. 233–243. 15 October 2023. PubMed. 10320942.
  9. Dual-color superresolution imaging of genetically expressed probes within individual adhesion complexes. Hari. Shroff. Catherine G.. Galbraith. James A.. Galbraith. Helen. White. Jennifer. Gillette. Scott. Olenych. Michael W.. Davidson. Eric. Betzig. 18 December 2007. Proceedings of the National Academy of Sciences. 104. 51. 20308–20313. 10.1073/pnas.0710517105. 18077327. 2154427 . 2007PNAS..10420308S . free .
  10. Live-cell photoactivated localization microscopy of nanoscale adhesion dynamics. Hari. Shroff. Catherine G.. Galbraith. James A.. Galbraith. Eric. Betzig. 15 May 2008. Nature Methods. 5. 5. 417–423. 10.1038/nmeth.1202. 18408726 . 5225950 .
  11. Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure. Gleb. Shtengel. James A.. Galbraith. Catherine G.. Galbraith. Jennifer. Lippincott-Schwartz. Jennifer M.. Gillette. Suliana. Manley. Rachid. Sougrat. Clare M.. Waterman. Pakorn. Kanchanawong. Michael W.. Davidson. Richard D.. Fetter. Harald F.. Hess. 3 March 2009. Proceedings of the National Academy of Sciences. 106. 9. 3125–3130. 10.1073/pnas.0813131106. 19202073. 2637278 . 2009PNAS..106.3125S . free .
  12. Rapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination. Thomas A.. Planchon. Liang. Gao. Daniel E.. Milkie. Michael W.. Davidson. James A.. Galbraith. Catherine G.. Galbraith. Eric. Betzig. 15 May 2011. Nature Methods. 8. 5. 417–423. 10.1038/nmeth.1586. 21378978 . 3626440 .
  13. New technologies in imaging. Catherine G.. Galbraith. Philipp J.. Keller. Eva. Nogales. 15 March 2013. Molecular Biology of the Cell. 24. 6. 669. 10.1091/mbc.e12-12-0867. 23486393. 3596229.
  14. Changes in single-molecule integrin dynamics linked to local cellular behavior. Khuloud. Jaqaman. James A.. Galbraith. Michael W.. Davidson. Catherine G.. Galbraith. Jennifer. Lippincott-Schwartz. 15 May 2016. Molecular Biology of the Cell. 27. 10. 1561–1569. 10.1091/mbc.E16-01-0018. 27009207. 4865314.
  15. James A.. Galbraith. Catherine G.. Galbraith. 1 October 2023. The International Journal of Biochemistry & Cell Biology. 163. 106455. 10.1016/j.biocel.2023.106455. 37586643 . 10528986 . 2308.01431 . October 1, 2024 .
  16. Web site: Cell Biology Seminar: Jim Galbraith and Cathy Galbraith. The Hub. 15 October 2023.
  17. Web site: ASCB/IFCB 2014—Looking at Small Things to Understand Big Things. Christina. Szalinski. 1 December 2014. 15 October 2023.
  18. Web site: Molecular Mechanisms of Cell Migration. dimensions.ai. 15 October 2023.
  19. Web site: NSF Award Search: Award # 1716316 - Facilitated transport of actin monomer and cytoskeletal remodeling. www.nsf.gov. 15 October 2023.
  20. Web site: Facilitated transport of actin monomer and cytoskeletal remodeling. dimensions.ai. 15 October 2023.

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