Catherine Day (biochemist) explained

Catherine Day
Alma Mater:	Massey University
Thesis1 Title:	Expression and characterisation of the n-terminal half of human lactoferrin
Thesis1 Url:	https://mro.massey.ac.nz/handle/10179/4125
Thesis1 Year:	1993

Catherine Louise Day is a New Zealand biochemist. She is currently a professor and was the head of the biochemistry department at the University of Otago.^[1]

Career

After a BSc at Massey University, Day completed a PhD entitled Expression and characterisation of the n-terminal half of human lactoferrin in 1993,^[2] also at Massey, before moving to the University of Otago where she rose to professor and head of department.^[1]

She has received funding from the Health Research Council of New Zealand^{[3] [4]} and Genesis Oncology Trust^[5] and is an associate editor for biochemistry and biophysics of the Royal Society's Open Science Journal.^[6]

Awards

Day won the Otago School of Medical Sciences' top award for 2010.

Selected works

• Chen, Lin, Simon N. Willis, Andrew Wei, Brian J. Smith, Jamie I. Fletcher, Mark G. Hinds, Peter M. Colman, Catherine L. Day, Jerry M. Adams, and David CS Huang. "Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function." Molecular Cell 17, no. 3 (2005): 393–403.^[7]
• Van Delft, Mark F., Andrew H. Wei, Kylie D. Mason, Cassandra J. Vandenberg, Lin Chen, Peter E. Czabotar, Simon N. Willis et al. "The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized." Cancer cell 10, no. 5 (2006): 389–399.^[8]
• Verhagen, Anne M., John Silke, Paul G. Ekert, Miha Pakusch, Hitto Kaufmann, Lisa M. Connolly, Catherine L. Day et al. "HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins." Journal of Biological Chemistry 277, no. 1 (2002): 445–454.^[9]
• Czabotar, Peter E., Erinna F. Lee, Mark F. van Delft, Catherine L. Day, Brian J. Smith, David CS Huang, W. Douglas Fairlie, Mark G. Hinds, and Peter M. Colman. "Structural insights into the degradation of Mcl-1 induced by BH3 domains." Proceedings of the National Academy of Sciences 104, no. 15 (2007): 6217–6222.^[10]

External links

• • • Institutional homepage

Notes and References

1. Web site: Profile, Department of Biochemistry, University of Otago, New Zealand . Otago.ac.nz . 16 December 2017.
2. Day . Catherine . 1993 . Doctoral thesis . Expression and characterisation of the n-terminal half of human lactoferrin . Massey Research Online, Massey University . 10179/4125.
3. Web site: Professor Catherine Day | Health Research Council . Hrc.govt.nz . 16 December 2017.
4. Web site: Rudd . Allison . 2011-02-04 . School of medical sciences names researcher of year . 2024-08-10 . Otago Daily Times Online News . en.
5. Web site: Monday 4 December 2017, Otago researchers gain new insights into inflammatory signalling mechanisms implicated in cancer, News and events, Department of Biochemistry, University of Otago, New Zealand . Otago.ac.nz . 4 December 2017 . 16 December 2017.
6. Web site: Biochemistry and Biophysics | Open Science . Rsos.royalsocietypublishing.org . 16 December 2017 . https://web.archive.org/web/20171216201254/http://rsos.royalsocietypublishing.org/biochemistry-and-biophysics . 16 December 2017 . dead .
7. Chen. Lin. Willis. Simon N.. Wei. Andrew. Smith. Brian J.. Fletcher. Jamie I.. Hinds. Mark G.. Colman. Peter M.. Day. Catherine L.. Adams. Jerry M.. Huang. David C. S.. 2005-02-04. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Molecular Cell. 17. 3. 393–403. 10.1016/j.molcel.2004.12.030. 1097-2765. 15694340. free.
8. van Delft. Mark F.. Wei. Andrew H.. Mason. Kylie D.. Vandenberg. Cassandra J.. Chen. Lin. Czabotar. Peter E.. Willis. Simon N.. Scott. Clare L.. Day. Catherine L.. Cory. Suzanne. Adams. Jerry M.. November 2006. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. Cancer Cell. 10. 5. 389–399. 10.1016/j.ccr.2006.08.027. 1535-6108. 2953559. 17097561.
9. Verhagen. Anne M.. Silke. John. Ekert. Paul G.. Pakusch. Miha. Kaufmann. Hitto. Connolly. Lisa M.. Day. Catherine L.. Tikoo. Anjali. Burke. Richard. Wrobel. Carolyn. Moritz. Robert L.. 2002-01-04. HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins. The Journal of Biological Chemistry. 277. 1. 445–454. 10.1074/jbc.M109891200. 0021-9258. 11604410. free.
10. Czabotar. Peter E.. Lee. Erinna F.. van Delft. Mark F.. Day. Catherine L.. Smith. Brian J.. Huang. David C. S.. Fairlie. W. Douglas. Hinds. Mark G.. Colman. Peter M.. 2007-04-10. Structural insights into the degradation of Mcl-1 induced by BH3 domains. Proceedings of the National Academy of Sciences of the United States of America. 104. 15. 6217–6222. 10.1073/pnas.0701297104. 0027-8424. 1851040. 17389404. 2007PNAS..104.6217C . free.