| Castelsantangelo sul Nera | |
| Official Name: | Comune di Castelsantangelo sul Nera |
| Coordinates: | 42.9°N 22°W |
| Region: | Marche |
| Province: | Macerata (MC) |
| Frazioni: | Gualdo, Macchie, Nocelleto, Nocria, Pian dell'Arco, Rapegna, Spina di Gualdo, Vallinfante |
| Mayor: | Mauro Falcucci |
| Area Total Km2: | 71.2 |
| Population Footnotes: | [1] |
| Population Total: | 281 |
| Population As Of: | 31 December 2015 |
| Population Demonym: | Castellani |
| Elevation M: | 760 |
| Saint: | St. Stephen |
| Day: | 26 December |
| Postal Code: | 62030 |
| Area Code: | 0737 |
Castelsantangelo sul Nera is a comune (municipality) in the Province of Macerata in the Italian region of Marche, located about 90km (60miles) southwest of Ancona and about 50km (30miles) southwest of Macerata. The source of the Nera River is located in the communal territory.