These are the number-one singles of 1966 according to the Top 100 Singles chart in Cashbox magazine
| Issue Date | Song | Artist |
|---|---|---|
| January 1 | We Can Work It Out | The Beatles |
| January 8 | ||
| January 15 | ||
| January 22 | ||
| January 29 | Simon & Garfunkel | |
| February 5 | Barbara Ann | The Beach Boys |
| February 12 | Lou Christie | |
| February 19 | ||
| February 26 | Nancy Sinatra | |
| March 5 | SSgt. Barry Sadler | |
| March 12 | ||
| March 19 | ||
| March 26 | ||
| April 2 | The Rolling Stones | |
| April 9 | Daydream | The Lovin' Spoonful |
| April 16 | The Righteous Brothers | |
| April 23 | ||
| April 30 | Good Lovin' | The Young Rascals |
| May 7 | Monday, Monday | The Mamas & the Papas |
| May 14 | ||
| May 21 | ||
| May 28 | Percy Sledge | |
| June 4 | The Mindbenders | |
| June 11 | Paint It, Black | The Rolling Stones |
| June 18 | Frank Sinatra | |
| June 25 | Paperback Writer | The Beatles |
| July 2 | ||
| July 9 | Hanky Panky | Tommy James and the Shondells |
| July 16 | ||
| July 23 | Wild Thing | The Troggs |
| July 30 | Napoleon XIV | |
| August 6 | Sam the Sham & the Pharaohs | |
| August 13 | Summer in the City | The Lovin' Spoonful |
| August 20 | ||
| August 27 | Sunny | Bobby Hebb |
| September 3 | Sunshine Superman | Donovan |
| September 10 | Yellow Submarine | The Beatles |
| September 17 | The Supremes | |
| September 24 | Cherish | The Association |
| October 1 | ||
| October 8 | ||
| October 15 | The Four Tops | |
| October 22 | 96 Tears | Question Mark & the Mysterians |
| October 29 | The Monkees | |
| November 5 | ||
| November 12 | Poor Side of Town | Johnny Rivers |
| November 19 | Good Vibrations | The Beach Boys |
| November 26 | Winchester Cathedral | The New Vaudeville Band |
| December 3 | The Supremes | |
| December 10 | Winchester Cathedral | The New Vaudeville Band |
| December 17 | ||
| December 24 | I'm a Believer | The Monkees |
| December 31 |